In this paper the spatial distribution ofwater quality in Lake Manzala was mappedfrom water samplev collectedfrom 20 sites over the lake in May 2006. The investigated parameters of water incorporated water turbidity, total phosphorus and Chlorophyll ‘a’. Spherical models were employed to spatially model water quality variabilityfor each of the measured variables. The geostatistical analysis fitted variograms and used interpolation of measurements over the whole lake to plot spatial patterns of water properties from defined transects in the lake. It was found that the southeastern portion of the lake adjacent to Bahr El Baqar outlet was the most deteriorated region in the lake due to excessive loadings of untreated sewage. The results indicated significant local concentration occurred along the SE-NW and E- W axes.